Regenerative medicine: targeted genome editing in vivo

Author: Wang, Lixia ¹ Liu, Guang-Hui ¹ Wu, Jun ² Belmonte, Juan Carlos Izpisua ² Fang, Weiwei ³ Liu, Guang-Hui ⁴ Liu, Guang-Hui ⁵
Institute:

1. Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, Beijing 100101, Peoples R China.

2. Salk Inst Biol Studies, Gene Express Lab, La Jolla, CA 92037 USA.

3. Beijing Hosp, Minist Hlth, Beijing 100730, Peoples R China.

4. Beijing Inst Brain Disorders, Beijing 100069, Peoples R China.

5. Ctr Mol & Translat Med, Beijing 100101, Peoples R China.
Submit Time:2016-05-12 08:40:40

Abstract: The CRISPR/Cas system has proven to be a powerful gene editing tool both in vitro and in vivo. A recent flurry of studies of in vivo gene editing using the CRISPR/Cas system bring bright prospects in creating animal models and targeted gene therapy of human genetic diseases.

STEM-CELL CLONES CRISPR-CAS9 DISEASE

Journal: CELL RESEARCH
Subject: Biology >> Biophysics >> Cell Biology
Cite as: ChinaXiv:201605.01464 (or this version ChinaXiv:201605.01464V1)
DOI:10.12074/201605.01464V1
CSTR:32003.36.ChinaXiv.201605.01464.V1
Recommended references： Wang, Lixia,Liu, Guang-Hui,Wu, Jun,Belmonte, Juan Carlos Izpisua,Fang, Weiwei,Liu, Guang-Hui,Liu, Guang-Hui.(2016).Regenerative medicine: targeted genome editing in vivo.CELL RESEARCH.[ChinaXiv:201605.01464] (Click&Copy)

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2016-05-12 08:40:40

ChinaXiv:201605.01464V1

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