CRISPR/Cas9 and TALE: beyond cut and paste

作者： Deng, Liping ¹ Ren, Ruotong ¹ Liu, Guang-Hui ¹ Wu, Jun ² Suzuki, Keiichiro ² Belmote, Juan Carlos Izpisua ² Liu, Guang-Hui ³ Liu, Guang-Hui ⁴
作者单位：

1. Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, Beijing 100101, Peoples R China.

2. Salk Inst Biol Studies, Gene Express Lab, La Jolla, CA 92037 USA.

3. Beijing Inst Brain Disorders, Beijing 100069, Peoples R China.

4. CMTM, Ctr Mol & Translat Med, Beijing 100101, Peoples R China.
提交时间：2016-05-12 08:40:39

摘要: Nuclease-based genome editing has proven to be a powerful and promising tool for disease modeling and gene therapy. Recent advances in CRISPR/Cas and TALE indicate that they could also be used as a targeted regulator of gene expression, as well as being utilized for illuminating specific chromosomal structures or genomic regions.

STEM-CELL CLONES TRANSCRIPTION VISUALIZATION SPECIFICITY IPSCS

期刊： PROTEIN & CELL
分类： 生物学 >> 生物物理学 >> 细胞生物学
引用： ChinaXiv:201605.01385 (或此版本 ChinaXiv:201605.01385V1)
DOI:10.12074/201605.01385V1
CSTR:32003.36.ChinaXiv.201605.01385.V1
推荐引用方式： Deng, Liping,Ren, Ruotong,Liu, Guang-Hui,Wu, Jun,Suzuki, Keiichiro,Belmote, Juan Carlos Izpisua,Liu, Guang-Hui,Liu, Guang-Hui.(2016).CRISPR/Cas9 and TALE: beyond cut and paste.中国生物工程预印本出版平台.[ChinaXiv:201605.01385] (点此复制)

版本历史

[V1]

2016-05-12 08:40:39

ChinaXiv:201605.01385V1

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