Subjects: Biology >> Botany >> Applied botany submitted time 2021-12-19 Cooperative journals: 《广西植物》
Abstract： Herba Xanthii is a traditional folk medicinal plant.The 50% ethanol eluting faction of Xanthium mongolicum in Jiangxi had significant activity to inhibit necroptosis. In order to investigate the chemical constituents, the active fractions of X. sibiricum were isolated and purified by various chromatographic methods such as repeated silica gel column chromatography, Sephadex LH-20 column chromatography, preparative high performance liquid chromatography and recrystallization to yield 14 compounds. Their structures were established on the basis of NMR, MS spectraoscopic analyses and comparison with lirerature date. Fourteen compounds were isolated from the active part and identified as hydroxydihydrobovolide(1), raspberry ketone(2), salicyl alcohol(3), 4-hydroxyl-acetophenone(4), 4-hydroxybenzaldehyde(5), ethyl caffeate(6), ferulaldehyde(7), isoscopletin(8), 3,3'-bis(3,4-dihydro-4-hydroxy-6 -methoxy-2H-1-benzopyran)(9)，axillarin (10)，quercetin (11)，(+) pinoresinol(12)， β-sitosterol(13) and palmatic acid(14). Compounds 1, 2, 3, 4, 7, 8, 9, 10 were isolated from Xanthium mongolicum for the first time．
Subjects: Biology >> Botany >> Applied botany submitted time 2021-04-13 Cooperative journals: 《广西植物》
Abstract： Cinnamomi Ramulus is a traditional chinese medicine commonly used in clinic. The ethanol extracts of Cinnamomi Ramulus had found the physiological activity to inhibit necroptosis in the previous studies. In order to clarify the chemical constituents of the plant and provide scientific basis for the rational development and sustainable utillization of the plant resources, the75% ethanol extracts of Cinnamomi Ramulus were isolated and purified by various chromatographic methods such as macroporous adsorption resin, silica gel, Sephadex LH-20 and preparative HPLC to yield 13 compounds. Their structures were identified by physicochemical properties and various spectral data analyses as abscisic acid(1), grasshopper ketone (2), 2,3-dihydroxy-1-(4-hydroxy-3,5- dimethoxyphenyl)-1-propanone (3), erythro-type-1,2,3- trihydr- oxyphenylpropane (4), 1-phenyl-1,3-propanediol (5), coumarin (6), cinnamic acid (7), p-hydroxycinnamic acid (8), o-hydroxycinnamic acid (9), o-metho- xycinnamic acid (10), cinnamaldehyde (11), ferulic acid (12) , ethyl caffeic acid (13). Among them, 1-5, 12 and 13 were isolated from the plant for the first time.
Subjects: Biology >> Botany >> Applied botany submitted time 2020-10-20 Cooperative journals: 《广西植物》
Abstract：毛梗豨莶草(Siegesbeckia glabresce)的乙酸乙酯萃取部位具有显著的抑制细胞坏死性凋亡(necroptosis)的活性。为明确毛梗豨莶草的活性成分，对毛梗豨莶草乙酸乙酯萃取部位进行了化学成分分离。采用正相硅胶柱色谱谱( 二氯甲烷∶甲醇20∶1～0∶1)、反相ODS柱色谱(30%～100% 甲醇)，Sephadex LH-20柱色谱、重结晶等方法进行分离和纯化，根据理化性质和波谱数据进行结构鉴定。从毛梗豨莶乙酸乙酯部位分离并鉴定了9个化合物，分别为3,7-二甲氧基槲皮素（1），芹菜素（2），奥卡宁（3），okanin-4'-O-β-D-6''-trans-p-coumaroylglucoside（4），1H-Indole-3-carbaldehyde（5），对羟基苯甲醛（6），3,5-二甲氧基-4-羟基苯甲醛（7），3,4-divanillyltetrahydrofuran（8），buddlenol D（9）。除化合物1和6外，其余7个化合物均为首次从豨莶属植物中分离得到。
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