Subjects: Biology >> Other Disciplines of Biology submitted time 2024-02-07 Cooperative journals: 《应用力学学报》
Abstract：
Due to the changes of modern lifestyles and the aging of the population,the incidence of spinal diseases has increased dramatically in recent years.Biomechanics research is an important part of the evaluation of spine related diseases.It is always an important means to explore the biomechanics of spine through modeling and simulation.At present,the combination of musculoskeletal model and finite element method has become a research hotspot in spinal biomechanics.Therefore,this paper investigates domestic and foreign articles that use the combination of musculoskeletal model and finite element method to explore spinal biomechanical characteristics,systematically describes the clinical application progress of this method in spine related diseases.And the paper summarizes the modeling method based on this method.It includes the setting of parameters such as loading method,Young’s modulus,Poisson’s ratio,and the application of this method in the evaluation of spine related diseases.The results show that based on musculoskeletal dynamics and finite element method,it provides a multi-scale evaluation method for exploring the stress,strain and IDP at the spinal tissue level during human body movement.However,this method currently has problems such as long model construction time,single research action and insufficient validation of model validity,which is the direction of future research in the field of spinal biomechanics.
Subjects: Biology >> Other Disciplines of Biology submitted time 2023-12-18 Cooperative journals: 《应用力学学报》
Abstract：
To study the response characteristics of different parts of spine under whole body vibration,a three-dimensional finite element model of the upper body was established based on the anatomical structure of human body,including head,spine,rib and pelvis.The 30-order modes of the model and different numbers of spinal segments(L3-L4,L1-L5 and C1-L5)were extracted by modal method,and the acceleration of each spinal segment in the X,Y and Z directions under the excitation of 0-20 Hz white noise in the vertical direction was calculated by random response method.It is found that the first mode of the upper body of the sitting body is in the front and back directions,and the second mode is in the left and right directions.The first-order vertical natural frequencies of all models are similar to the literature results,and the peak frequencies of the average acceleration responses of all intervertebral discs are in the range of 4- 6 Hz vertical frequencies of sitting human bodies,thus proving the validity of the model.It is found that the modes with great influence on human vibration are mainly distributed within 0-12 Hz.The root mean square of disc Z acceleration decreases from cervical vertebra to lumbar vertebra,while the root mean square of X acceleration is the smallest near T7-T8 and the largest at L4-L5.The dynamic model created in this paper not only can be used to study the internal dynamic response law of the human body more accurately,but also has fast response calculation,which provides a research method and theoretical basis for further improving ride comfort and reducing spinal diseases.
Subjects: Biology >> Other Disciplines of Biology submitted time 2023-09-05 Cooperative journals: 《古脊椎动物学报》
Abstract： Bothriolepis sinensis Chi 1940, mainly based on anterior median dorsal plates from the Middle Devonian Tiaomachien Formation of Hunan, is the first Paleozoic vertebrate taxon erected in China. Although additional materials of B. sinensis from the type locality were described by Lu in 1988, its morphology and phylogeny remain poorly understood. In this study, we complemented the morphology of the skull and trunk armor of B. sinensis based on Chi’s specimens housed in the Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, and several previously undescribed specimens in the Geological Museum of China. Bothriolepis sinensis differs from other Bothriolepis in the following combination of characteristics: enlarged supraotic thickening, length/width ratio of head shield 1.4–1.6, broad orbital fenestra (greater than 1/3 of the head shield width), and fan-shaped preorbital recess. The phylogenetic analysis did not place B. askinae in the most basal position of the genus and revealed that B. sinensis and B. kwangtungensis consistently from a monophyletic group characterized by their slender proximal segment of the pectoral fin (length/width ratio greater than 7). A majority of Chinese Bothriolepis species (B. niushoushanensis, B. lochangensis, B. tungseni, B. kwangtungensis and B. sinensis) were clustered in a clade characterized by the pectoral pit-line on the ventral central plate 1 extending to the ventral central plate 2. The paleogeographic reconstruction using the data from the DeepBone platform showed that Bothriolepis had its oldest occurrences in South China and East Gondwana in Eifelian, dispersed rapidly worldwide, and then diversified across the coasts of the Rheic Ocean.
Subjects: Biology >> Other Disciplines of Biology submitted time 2023-08-23 Cooperative journals: 《中国科学院院刊》
Abstract： The Kunming-Montreal Global Biodiversity Framework adopted by the United Nations Convention on Biological Diversity (CBD) at the Conference of Parties (COP15) has set a series of targets, including protecting at least 30% of the oceans by 2030 worldwide. In China, how to build a marine ecological civilization in synergy with the targets has become an important issue. This study analyzes the necessity of accelerating the construction of marine protected areas in China from the perspectives of adapting to international trends, fulfilling the responsibilities of international conventions, safeguarding maritime rights and interests, and implementing the maritime power and strategy. The feasibility is discussed from the aspects of national financial support, policy support and marine comprehensive strength support. It summarized and sorted out the problems in the construction of marine protected areas in China, including small scale, slow development and the large gap between domestic and international communities, the concept of marine management by land-based thinking, and the lack of land-sea classification, the imperfect management system, the backward technical standards and so on. With a problem-oriented approach, this study puts forward some countermeasures and suggestions to improve the management system of marine protected areas in China, optimize and integrate offshore protected areas, promote the construction of the South China Sea National Park, and focus on global marine protection and governance.
Subjects: Biology >> Other Disciplines of Biology submitted time 2023-04-20
Abstract：在古人类研究中，骨骼，尤其是头骨性状的测量是获得标本特征信息的主要手段。随着技术的发展，CT技术及三维复原技术为骨骼测量带来了巨大的便利。其中Mimics软件作为常用的三维重建软件之一，在复原过程中为使用者提供了低、中、高、最佳这四种精度的选择。我们希望获知在不同复原精度得到的模型上进行测量得到的结果存在何种程度的差异，以便在未来研究过程中选择最合适的标准。在本研究中，我们选择了顶骨矢状弦、颅周、头盖面积、乳突小房表面积、颅容量、乳突小房体积这六项性状的测量数据作为检测指标，计算同一批现代人标本在Mimics中采用不同精度复原得到的模型间测量数值的差异，根据Mimics的复原模型简化规则，我们选择未精简的最佳精度模型作为标准进行非参数检验、配对t检验及计算测量差异占比。结果表明，这六项的不同简化精度模型测量数据与最佳精度模型测量数据的非参数检验及配对t检验均具有显著差异。顶骨矢状弦、颅周、头盖面积、颅容量的测量差异占比基本均小于3%，而乳突小房表面积的低精度测量差异占比可达到50%以上，乳突小房体积低精度测量差异占比可达120%以上。除去简化过程造成的模型表面膨胀外，乳突小房的多气房结构造成不同精度之间存在的绝对差异比上一整体体量小区域而形成的巨大相对差异提示我们，在三维模型的测量中，对于头骨内部腔窦这样小体量表面粗糙的部分的复原精度选择及数据比较需要格外谨慎。
Subjects: Biology >> Other Disciplines of Biology Subjects: Computer Science >> Computer Application Technology submitted time 2023-02-09
Abstract：
Circular RNA (circRNAs) may mediate mRNA expression as miRNA sponge. Since the community has paid more attention on circRNAs, a lot of circRNA databases have been developed for plant. However, a comprehensive collection of circRNAs in crop response to abiotic stress is still lacking. In this work, we applied a big-data approach to take full advantage of large-scale sequencing data, and developed a rich circRNA resource: CropCircDB for maize and rice, later extending to incorporate more crop species. We also designed a metric: stress detections score, which is specifically for detecting circRNAs under stress condition. In summary, we systematically investigated 244 and 288 RNASeq samples for maize and rice, respectively, and found 38 785 circRNAs in maize, and 63 048 circRNAs in rice. This resource not only supports user-friendly JBrowser to visualize genome easily, but also provides elegant view of circRNA structures and dynamic profiles of circRNA expression in all samples. Together, this database will host all predicted and validated crop circRNAs response to abiotic stress.
Peer Review Status:
Awaiting Review
Subjects: Biology >> Other Disciplines of Biology submitted time 2022-12-04
Abstract：
Inflammation is one of the crucial pathological factors of numerous diseases. It is critical to search for new strategies to decrease inflammation-produced damage. Our previous study has reported that Koisio technology-produced cell culture media produced increased antioxidant capacity of cell cultures. Since oxidative stress plays a significant role in inflammation-produced tissue injury, in our current study we used a mouse model of acute colon inflammation to test our hypothesis that Koisio technology-produced water may decrease inflammation-produced tissue damage. Our study has obtained evidence supporting the hypothesis: First, Koisio technology-produced water significantly attenuated inflammation-induced shortening of colon length in the mouse model of Dextran Sulfate Sodium salt (DSS)-induced acute colon inflammation; second, Koisio technology-produced water significantly attenuated colon inflammation-induced increase in DAI in the mouse model; third, Koisio technology-produced water significantly attenuated colon inflammation-induced increase in the Spleen Index in the mouse model; and fourth, Koisio technology-produced water significantly attenuated the increases in the myeloperoxidase (MPO) activity and the Eosinophil peroxidase (EPO) activity in the mouse model. Collectively, our study has provided novel evidence suggesting that Koisio technology-produced water can decrease inflammation-induced tissue damage in the mouse model of acute colon inflammation.
Peer Review Status:Awaiting Review
Subjects: Psychology >> Applied Psychology Subjects: Biology >> Other Disciplines of Biology submitted time 2021-08-11
Abstract： " " "
Peer Review Status:Awaiting Review
Subjects: Biology >> Other Disciplines of Biology submitted time 2018-12-04 Cooperative journals: 《古脊椎动物学报》
Abstract： Abstract Here the posterior cranial portion of the tetrapodomorph Tungsenia from the Lower Devonian (Pragian, ~409 million years ago) of Yunnan, southwest China, is reported for the first time. The pattern of posterior skull roof and the morphology of the otoccipital region of the neurocranium are described in detail, providing precious insight into the combination of cranial characters of the earliest known tetrapodomorph to date. The posterior cranium of Tungseniadisplays a mosaic of features previously linked either to basal dipnomorphs such as Youngolepis(e.g., the well-developed subjugular ridge, the strong adotic process, and the poorly developed fossa bridgei) or to typical tetrapodomorphs (e.g., the lateral dorsal aortae commenced from the median dorsal aorta postcranially). The independent ventral arcual plate is also found in the advanced tetrapodomorph Eusthenopteron. The new endocranial material of Tungsenia further fills in the morphological gap between Tetrapodomorpha (tetrapod lineage) and Dipnomorpha (lungfish lineage) and unveils the sequence of character acquisition during the initial diversification of the tetrapod lineage. The new phylogenetic analysis strongly supports the basalmost position of Tungsenia amongst the tetrapod lineage.
Subjects: Biology >> Other Disciplines of Biology submitted time 2018-12-04 Cooperative journals: 《古脊椎动物学报》
TAN Chao
DAI Hui
HE Jian-Jun
ZHANG Feng
HU Xu-Feng
YU Hai-Dong
LI Ning
WEI Guang-Biao
PENG Guang-Zhao
YE Yong
ZHANG Qian-Nan
REN Xin-Xin
YOU Hai-Lu
Abstract： A cervical vertebra recovered from the Middle Jurassic Lower Member of the Shaximiao Formation in Town of Puan, Yunyang County, Chongqing is assigned to an species undeterminata of the sauropod dinosaur Omeisaurus based on morphological and comparative study. The centrum of this mid-cervical is much hollower than solider with extremely developed fossa/foramen complex and has a high ratio (5.05) of its anteroposterior length excluding the articular ball divided by the mean value of the posterior articular surface mediolateral width and dorsoventral height. Additional features of this cervical include central length about twice the total vertebral height, a prominent midline keel on the central ventral surface, deep and long cavities bounded by centroprezygapophyseal lamina/ intraprezygapophyseal lamina and centropostzygapophyseal lamina/intrapostzygapophyseal lamina, respectively, a coel on the dorsal half of the postzygapophyseal centrodiapophyseal fossa, long prone epipophysis extending beyond the postzygapophysis facet, anteroposteriorly length of the neural spine about half the length of the centrum, and concavities on the anterior one third lateral surface of the neural spine. Therefore, this discovery reveals new morphological information on Omeisaurus, and this Omeisaurus-bearing Puan dinosaur quarry represents the easternmost occurrence of this genus.
Subjects: Biology >> Other Disciplines of Biology submitted time 2018-10-23 Cooperative journals: 《干旱区地理》
Abstract： 以相关领域关于土体蒸发模型研究成果为基础，结合岩土工程蒸发过程的特点，对确定土体潜在蒸发量方法的发展及现状进行介绍，并对每种理论模型的适用条件及参数的确定等进行分析。得出以下认识：（1）特定的地区、气候条件下，通过多种理论模型对比分析，确定相对合适的理论模型估算潜在蒸发量是必要的。（2）气象参数的区域性很明显，即使是具有相似气候特征的小区域，不同的气象站提供的气象资料反演的气象参数也不相同，故根据气象资料反演得到的气象参数要进行修正。（3）现有蒸发测量技术应用于岩土工程的蒸发测量中有待进一步深入研究发展。提出该课题在岩土工程领域今后的研究方向，包括土体稳定蒸发阶段蒸发机制、蒸发的滞后效应、夜间土体水分变化对蒸发的影响、通用蒸发模型的建立及实测蒸发量的尺度效应等。
Subjects: Biology >> Other Disciplines of Biology submitted time 2018-07-18 Cooperative journals: 《古脊椎动物学报》
Abstract： This paper reviews recent works on the age of Chinese terrestrial Permo-Triassic strata, mainly based on the isotopic dating and the tetrapod correlation. For the application of U-Pb dating methods for the stage-level division of Permo-Triassic strata, the best method is the Thermal Ionization Mass Spectrometer (TIMS), while the Secondary Ion Mass Spectroscopy (SIMS) can be used for many cases; however, the most popular Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICPMS), which has nearly 4% error (>8 Myr), is of little use (Li et al., 2015).
Subjects: Biology >> Other Disciplines of Biology submitted time 2018-07-18 Cooperative journals: 《古脊椎动物学报》
Abstract： Here we discribe a new ootypes of prismatoolithids found from the Late Cretaceous Jiangjunding Formation in the Laiyang Basin, Shandong Province. On the basis of characters such as elongate ovoids, smooth eggshell surface, relatively thinner eggshell thickness, prismatic eggshell units, slender pores in radial section of eggshell and little pores with round or irregular shapes in tangeital section of eggshell, we erect one new oogenus and one new oospecies: Laiyangoolithus lixiangensis oogen. et oosp. nov. The discovery of L. lixiangensis not only enriches the diversity and composition of the Laiyang Dinosaur Egg Fauna, but the paleogeographic distribution of primatoolithids as well. In addition, it provides more paleontological materials for the study of the diversity and paleogeographic distribution of troodontids in China.
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