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1. chinaXiv:202108.00084 [pdf]

A Temnospondyl Tooth from the Middle Triassic of the Ordos Basin, Shaanxi Province

WU Rui; TU Li; HAN Feng-Lu
Subjects: Biology >> Zoology

An isolated large temnospondyl tooth was discovered from the Middle Triassic Tongchuan Formation, Weibei Oilfield, Ordos Basin, Shaanxi Province of China. Compared with the teeth of crocodylomorphs, plesiosaurs and temnospondyls, the tooth can be referred to temnospondyl based on the following features: the crown is elongated and recurved with a circular cross-section; there are no denticles or carinae on the crown; well-marked apicobasal grooves are shown on the crown surface. This tooth represents the first temnospondyl found in the Middle Triassic Tongchuan Formation and is the youngest fossil record of temnospondyls in the North China Block.

submitted time 2021-08-11 From cooperative journals:《古脊椎动物学报》 Hits4249Downloads276 Comment 0

2. chinaXiv:202108.00085 [pdf]

A cuboid bone of a large Late Miocene elasmothere from Qingyang, Gansu, and its morphological significance

ZHANG Xiao-Xiao; SUN Dan-Hui
Subjects: Biology >> Zoology

A cuboid specimen collected from the Late Miocene stratum at Qingyang, Gansu, China is described here. The size of the Qingyang specimen is comparatively huge, even larger than the average size of Elasmotherium caucasicum collected from Nihewan, Hebei, China. The morphology of the Qingyang specimen is identical to that of other specimens of Elasmotheriini; thus, the Qingyang specimen belongs to a huge elasmothere, most probably Sinotherium. By comparison with extant rhino species, the complex of the main body and the apophysis exhibit functional significance. The angle between the frontal plate of the cuboid and the main axis of the apophysis can suggest the ecological conditions occupied by an elasmothere. From analysis of the morphology of the cuboid, Sinotherium and the more derived elasmotheres probably lived in forested or wooded environments, differing from the previous hypothesis of their paleoenvironment.

submitted time 2021-08-11 From cooperative journals:《古脊椎动物学报》 Hits3721Downloads268 Comment 0

3. chinaXiv:202108.00059 [pdf]

创伤后应激障碍的组蛋白修饰机制

张萦倩; 赵光义; 韩雨薇; 张静怡; 曹成琦; 王力; 张昆林
Subjects: Psychology >> Applied Psychology

创伤后应激障碍是一种具有复杂病因学的精神疾病,多发生于个体受到重大创伤事件后。创伤后应激障碍的发生发展过程受到环境和遗传易感性的共同作用,存在着较大的个体差异;而表观遗传学作为一门研究多变环境因素调控基因表达的可遗传变化的学科,近年来在创伤后应激障碍的研究中受到越来越多的重视。表观遗传机制之一——组蛋白修饰机制在创伤后应激障碍的发生中起着重要作用,并且由于组蛋白修饰可以受到多种酶的调控,其灵活的可逆化和精细调控为相应的药物研发提供了可能性和便利。因此,深入探讨创伤后应激障碍的组蛋白修饰机制,对于相关疾病的临床治疗及药物研发具有十分重要的意义。当前创伤后应激障碍的组蛋白修饰研究主要使用动物模型,临床研究较少;组蛋白的类型则主要关注组蛋白H3和H4乙酰化;此外,同以往的研究结果一致,组蛋白修饰水平的变化主要发生在前额叶、海马体和杏仁核区域,参与免疫系统、血清素系统和神经肽Y能系统等相关通路的调节。当前PTSD组蛋白修饰的研究结果间还存在较大的异质性,未来的研究应采用更加一致和实用的分析和报道方法,以最大限度地发挥研究的影响。

submitted time 2021-08-11 Hits5401Downloads316 Comment 0

4. chinaXiv:202108.00058 [pdf]

Metagenomic evidence for the coexistence of SARS and H1N1 in patients from 2007-2012 flu seasons

Qi Liu; Zhenglin Du; Sihui Zhu; Wenming Zhao; Hua Chen; Yongbiao Xue
Subjects: Biology >> Microbiology

By re-analzying public metagenomic data from 101 patients infected with influenza A virus during the 2007-2012 H1N1 flu seasons in France, we identified 22 samples with SARS-CoV sequences. In 3 of them, the SARS genome sequences could be fully assembled out of each. These sequences are highly similar (99.99% and 99.7%) to the artificially constructed recombinant 5 SARS-CoV (SARSr-CoV) strains generated by the J. Craig Venter Institute in USA. Moreover, samples from different flu seasons have different SARS-CoV strains, and the divergence between these strains cannot be explained by natural evolution. Our study also shows that retrospective studies using public metagenomic data from past major epidemic outbreaks serves as a genomic strategy for the research of origins or spread of infectious diseases.

submitted time 2021-08-11 Hits6530Downloads818 Comment 0

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