Subjects: Biology >> Microbiology Subjects: Medicine, Pharmacy >> Preclinical Medicine submitted time 2021-08-11
Abstract： By re-analzying public metagemonic data from 101 patients infected with influenza A virus from the 2007-2012 flu seasons in France, we identified artificially constructed recombinant SARS-CoV (SARSr-CoV) sequences in 22 samples, among which three were fully assembled. These sequences are highly similar to the recombinant SARSr-CoV strains generated by the J. Craig Venter Institute in USA, indicating the coexistence of SARS and H1N1 in these patients, which may be caused by possible co-infection or contamination accident. Our analysis also suggests that re-analyzing public metagenomic data is useful for retrospective studies on past outbreaks of infectious diseases. "
Peer Review Status:
Awaiting Review
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