Subjects: Biology >> Bioengineering submitted time 2019-05-06
Abstract： " Terpenoids have considerable commercial value, but the production process is complex and the yield is low. It has become a hot spot to synthesize terpenoids from microorganism. Corynebacterium glutamicum contains a pathway to produce carotenoid, which is a natural advantage for the synthesis of terpenoids heterologously. The synthesis of terpenoids from C. glutamicum is summarized, including the terpenoids synthesis pathway in C. glutamicum, key enzymes and global regulatory mechanisms in this pathway. And the advances in this pathway in synthesis of monoterpenes, sesquiterpenes, and tetraterpenes are summarized. The problems and advice efficient synthesis of terpenoids by C. glutamicum is discussed.
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Subjects: Biology >> Bioengineering submitted time 2018-12-16 Cooperative journals: 《中国生物工程杂志》
Abstract：萜类化合物具有可观的商业价值，但生产过程复杂，产量低，利用微生物异源合成萜类化合物已成为热点。谷氨酸棒状杆菌内含合成萜类色素的途径，具有异源合成萜类化合物的天然优势和研究前景。首次对谷氨酸棒状杆菌合成萜类化合物进行了综述，从萜类合成途径、关键酶和全局调控机制三个方面进行了途经介绍。概述了谷氨酸棒状杆菌中单萜、倍半萜、四萜类化合物的异源合成，并对利用谷氨酸棒状杆菌高效合成萜类化合物所需解决的问题进行讨论，为谷氨酸棒状杆菌高效合成萜类化合物提供建议。
Subjects: Biology >> Bioengineering submitted time 2017-07-24 Cooperative journals: 《中国生物工程杂志》
Abstract：槐糖脂是一种糖脂类生物表面活性剂，因其低毒性、生物可降解性、生物相容性及良好的生物活性而备受关注，利用球拟假丝酵母生产生物表面活性剂槐糖脂极大的加速了其产业化进程。对槐糖脂在球拟假丝酵母中的生物合成途径、关键酶的特点和基因工程改造假丝酵母合成新型生物表面活性剂的最新进展进行了综述。为扩展球拟假丝酵母作为糖脂化合物合成底盘细胞提供建议和前景分析。
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