Subjects: Medicine, Pharmacy >> Clinical Medicine Subjects: Biology >> Bioengineering Subjects: Physics >> Electromagnetism, Optics, Acoustics, Heat Transfer, Classical Mechanics, and Fluid Dynamics submitted time 2019-01-15
Qiang Tang
Wei Zou
Zuodong Sun
Kang Li
Wuyi Sun
Wenhua Wang
Yanli Xing
Xueping Yu
Jing Bai
Xiuying Teng
Yan Hou
Abstract： [Objective] Evaluate on the treatment efficacy and safety for transcranial magnetoelectric encephalopathy treatment instrument (brand name: AOBO Parkinson’s Treatment Instrument) treatmenting parkinson's disease. [Methods] Use methods of double center,randomized, double blind, self crossover, 22 Parkinson’s patients who met the inclusion criteria were randomly divided into A group and B group, then were carried on the curative effect analysis, and were observed therapeutic effect. [Results] The treatment group of 22 cases, basically cured in 0 cases, markedly effective in 9 cases, effective in 8 cases, ineffective in 5 cases. The total efficiency rate and total effective rate were 40.91% (9/22) or 77.27% (17/22) respectively. The control group of 22 cases, basically cured in 0 cases, markedly effective in 2 cases, effective in 3 cases, ineffective in 17 cases. The total efficiency rate and total effective rate were 9.09% (2/22) or 22.73% (5/22) respectively, the total effective rate and total effective rate in the treatment group were higher than those in the control group, the difference was statistically significant (P<0.05). Among them, the main symptoms of resting tremor, rigidity, bradykinesia, evaluation, the treatment group has significant difference (P<0.01); There was no significant difference in the control group (p>0.05); There was significant difference between the treatment group and the control group (p<0.05). [Conclusions] Transcranial magnetoelectric stimulation can significantly improve resting tremor, muscle rigidity, bradykinesia in patients with Parkinson’s disease and other symptoms, and the use of safety. "
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