Abstract:
The experiment was conducted to study to the effects of alfalfa saponin on growth performance, intestinal microflora, antioxidant ability and related enzyme mRNA expression in tissues of weaned piglets. A total of 24 crossed-bred (Landrace譒arge White) piglets with an average body weight of 8 kg were randomly assigned to 2 groups with 3 replicates each and 4 piglets in each replicate. The piglets in control group were fed a basal diet, and in alfalfa saponin group were fed the basal diet supplemented with 0.25% alfalfa saponin. The experiment lasted for 30 days after 10 days pre-experiment. The results showed as follows: 1) compared with control group, dietary alfalfa saponin significantly increased average daily gain (P<0.05) and significantly decreased the ratio of feed to gain (P<0.05) of weaned piglets. 2) Compared with control group, dietary alfalfa saponin significantly reduced pH in duodenum and cecum (P<0.05), significantly increased the numbers of Lactobacillus in duodenum, jejunum and cecum (P<0.05) of piglets. 3) Compared with control group, dietary alfalfa saponin significantly increased the activity of glutathion peroxidase (GSH-Px) and catalase (CAT) in liver and kidney (P<0.05), and significantly improved the mRNA expression level of GSH-Px in liver and jejunum as well as the mRNA expression level of CAT in duodenum and ileum (P<0.05) of piglets. In summary, dietary alfalfa saponin can enhance growth performance of weaned piglets, improve antioxidant ability in tissues and have a good benefit on intestinal microflora.